Description

tert-Butyl 4-(2-Ethoxy-2-oxoethyl)piperidine-1-carboxylate is a high-purity, protected piperidine derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its value lies in the orthogonal protection of the piperidine nitrogen and the functionalized side chain, enabling precise and controlled chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex molecular architectures for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its piperidine scaffold.
• Chemical Research & Development: A versatile reagent for constructing complex heterocycles and exploring new reaction pathways in medicinal chemistry.
• Peptidomimetics & Bioactive Molecule Construction: The protected amine and ester functionalities make it suitable for creating peptide analogs and other biologically active compounds.
• Ligand & Catalyst Development: Serves as a precursor for specialized ligands used in asymmetric catalysis and metal-organic frameworks.

Basic Information

Product Name	tert-Butyl 4-(2-Ethoxy-2-oxoethyl)piperidine-1-carboxylate
CAS No.	1003-40-3
Molecular Formula	C14H25NO4
Molecular Weight	271.35 g/mol
Synonyms	1-Boc-4-(2-Ethoxy-2-oxoethyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(2-ethoxy-2-oxoethyl)piperidine; 4-(Ethoxycarbonylmethyl)-1-N-Boc-piperidine; tert-Butyl 4-(carbethoxymethyl)-1-piperidinecarboxylate; 4-(2-Ethoxy-2-oxoethyl)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-(2-ethoxy-2-oxoethyl)piperidine; 1-Boc-4-(ethoxycarbonylmethyl)piperidine; Piperidine-1-carboxylic acid, 4-(2-ethoxy-2-oxoethyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Ethoxy-2-oxoethyl)piperidine-1-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.