Description

5-Azaspiro[2.4]heptane is a versatile and structurally unique nitrogen-containing heterocyclic building block. This compound is of significant value in advanced organic synthesis, particularly in pharmaceutical research and development. It serves as a critical scaffold for medicinal chemists seeking to create novel molecular entities with enhanced biological activity and pharmacokinetic properties. Industries such as agrochemicals and material science also utilize this specialized intermediate for creating complex, functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Scaffold: Used as a rigid, three-dimensional core structure for constructing compound libraries in drug discovery programs.
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, and insecticides that require specific spirocyclic architectures.
• Ligand and Catalyst Development: Acts as a building block for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal or mechanical properties.
• Academic and R&D Laboratories: Serves as a valuable reagent for methodological studies and the exploration of new chemical spaces in organic chemistry.

Basic Information

Item	Details
Product Name	5-Azaspiro[2.4]heptane
CAS No.	185-50-2
Molecular Formula	C6H11N
Molecular Weight	97.16 g/mol
Synonyms	1-Azaspiro[2.4]heptane; Azaspiroheptane; Spiro[cyclopropane-1,2'-pyrrolidine]; 1-Aza-4-spiro[2.4]heptane; 2,5-Diazabicyclo[2.2.1]heptane (related bicyclic system); 5-Azaspiro(2.4)heptane; NSC 102016
EINECS	Contact for details

Quality Control

Our 5-Azaspiro[2.4]heptane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The container should be kept tightly sealed to minimize exposure to atmospheric moisture and carbon dioxide.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.