Description

1-Azaspiro[4.5]Decane is a versatile and synthetically valuable nitrogen-containing heterocyclic compound, specifically a bridged bicyclic amine. This spirocyclic structure serves as a crucial pharmacophore and advanced intermediate in modern organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing drug candidates with spirocyclic cores, potentially targeting central nervous system (CNS) disorders, antimicrobials, and other therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the spirocyclic amine moiety can impart unique biological activity and stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Precursor: Employed in the synthesis of specialty polymers, dyes, and organic electronic materials that require rigid, three-dimensional amine components.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study enzyme function and protein-protein interactions.

Basic Information

Product Name	1-Azaspiro[4.5]Decane
CAS No.	176-80-7
Molecular Formula	C9H17N
Molecular Weight	139.24 g/mol
Synonyms	1-Azaspiro[4.5]decane; Azaspiro[4.5]decane; 1-Aza-spiro[4.5]decane; Spiro[cyclohexane-1,1'-pyrrolidine]; 1'-Azaspiro[cyclohexane-1,2'-pyrrolidine]; 2-Azaspiro[4.5]decane (common misnomer); 1-Azoniabicyclo[3.3.1]nonane (cation form); Contact for additional trade names and abbreviations.
EINECS	205-858-7

Quality Control

We supply 1-Azaspiro[4.5]Decane in various grades, including standard and high-purity, to meet diverse R&D and scale-up needs. Our products undergo rigorous quality testing (including HPLC, GC, NMR) to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all relevant specifications. We adhere to a cGMP-compliant quality management system where applicable, ensuring traceability and reliability for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere (nitrogen or argon), please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (GC / HPLC)	≥95.0% (Standard Grade), ≥98.0% (High Purity Grade)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.