Description

8-Azaspiro[4.5]decane is a versatile and valuable nitrogen-containing spirocyclic compound, serving as a crucial building block in advanced organic synthesis. Its unique bridged bicyclic structure makes it an essential intermediate for constructing complex molecular architectures with specific three-dimensional properties. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of central nervous system (CNS) active drugs, potential enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers, dendrimers, and other functional organic materials.
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes and tools to study biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring complex, rigid nitrogen heterocycles.

Basic Information

Product Name	8-Azaspiro[4.5]decane
CAS No.	176-64-7
Molecular Formula	C9H17N
Molecular Weight	139.24 g/mol
Synonyms	8-Azaspiro[4.5]decane; 1-Azaspiro[4.5]decane; Spiro[4.5]decan-8-amine; Azaspirodecane; NSC 102016; 1-Aza-spiro[4.5]decane; 8-Aza-spiro[4.5]decane
EINECS	205-861-6

Quality Control

Our 8-Azaspiro[4.5]decane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced analytical techniques such as GC, HPLC, and NMR. We are committed to meeting the stringent requirements of our global partners in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.