Description

1,6-Dioxaspiro[4.4]Nonane is a specialized spirocyclic acetal compound with the CAS registry number 176-25-0. This unique bicyclic structure makes it a valuable and versatile intermediate in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fragrance industries for applications requiring rigid, oxygen-containing frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially those requiring spirocyclic or constrained ether motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure can contribute to specific biological activity and stability.
• Fragrance and Flavor Chemistry: Acts as a precursor for creating unique musk-like or earthy odorants and flavor compounds due to its stable, oxygenated ring system.
• Material Science Research: Employed in the development of specialty polymers, resins, and ligands where the spiroacetal unit can impart specific physical or chemical properties.
• Organic Synthesis Reagent: Functions as a protected form of a diketone or diol, useful in multi-step synthetic routes for natural products and complex molecules.

Basic Information

Product Name	1,6-Dioxaspiro[4.4]Nonane
CAS No.	176-25-0
Molecular Formula	C7H12O2
Molecular Weight	128.17 g/mol
Synonyms	1,6-Dioxaspiro(4.4)nonane; Spiro[1,3-dioxolane-2,1'-cyclohexane]; 1,6-Dioxaspiro[4.4]nonane; Cyclohexanespiro-2'-(1,3-dioxolane); 2,2-Pentamethylene-1,3-dioxolane; 1,3-Dioxolane, 2,2-pentamethylene-; NSC 106977
EINECS	205-861-3

Quality Control

Our 1,6-Dioxaspiro[4.4]Nonane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters. We support cGMP and ISO standards for reliable, batch-to-batch consistency suitable for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.460
Density (g/mL at 20°C)	1.02 - 1.06

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.