Description

1-Oxa-7-Aza-Spiro[4.4]Nonane is a versatile spirocyclic heterocyclic compound featuring both ether and amine functionalities within a rigid bicyclic framework. This unique structure makes it a valuable and sophisticated building block in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Building Block: Used to introduce conformational constraint and modulate physicochemical properties in lead optimization programs.
• Agrochemical Research: Serves as a core structure in the synthesis of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: The spirocyclic amine moiety can be utilized in the design of novel chelating ligands and organocatalysts.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Academic & R&D Laboratories: Employed in methodological studies and the synthesis of complex natural product analogs.

Basic Information

Product Name	1-Oxa-7-Aza-Spiro[4.4]Nonane
CAS No.	176-12-5
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	1-Oxa-7-azaspiro[4.4]nonane; 7-Aza-1-oxaspiro[4.4]nonane; 1-Oxa-7-azaspiro(4,4)nonane; Oxa-aza-spiro[4.4]nonane; 1,7-Oxazaspiro[4.4]nonane (common misnomer); Spirocyclic ether-amine; Tetrahydro-1,7-epiminooxepin
EINECS	Contact for details

Quality Control

We supply 1-Oxa-7-Aza-Spiro[4.4]Nonane in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.