Description

2-Chloro-5-Fluoropyrimidin-4-One is a high-value fluorinated pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its unique halogenated structure makes it indispensable for constructing complex molecules with tailored biological and physical properties. This intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	2-Chloro-5-Fluoropyrimidin-4-One
CAS No.	155-12-4
Molecular Formula	C4H2ClFN2O
Molecular Weight	148.52 g/mol
Synonyms	4(1H)-Pyrimidinone, 2-chloro-5-fluoro-; 2-Chloro-5-fluoropyrimidin-4(3H)-one; 5-Fluoro-2-chloropyrimidin-4-ol; 2-Chloro-5-fluoro-4-hydroxypyrimidine; 2-Chloro-5-fluoro-4(1H)-pyrimidinone; 2-Chloro-5-fluoropyrimidin-4-ol; 155-12-4; 2-Chloro-5-fluoro-4-pyrimidinol
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoropyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.