Description

17-β-Estradiol 3,17-Dipropionate is a synthetic, long-acting ester derivative of the primary female sex hormone, estradiol. This compound is valued for its enhanced stability and prolonged pharmacological activity compared to the parent hormone, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily required by manufacturers in the pharmaceutical and life science research sectors for the development of hormone replacement therapies, veterinary medicines, and as a reference standard in analytical laboratories.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of long-acting estrogenic drugs and hormone replacement therapy (HRT) formulations.
• Veterinary Medicine: Used in the production of estrus synchronization agents and treatments for reproductive disorders in livestock.
• Research & Development: Serves as a high-purity reference standard and biochemical tool in endocrinology and metabolic disease research.
• Controlled-Release Drug Delivery: Utilized in the development of implantable or injectable sustained-release drug delivery systems due to its esterified, lipophilic nature.

Basic Information

Product Name	17-β-Estradiol 3,17-Dipropionate
CAS No.	113-38-2
Molecular Formula	C24H32O4
Molecular Weight	384.51 g/mol
Synonyms	Estradiol Dipropionate; 17β-Estradiol 3,17-Dipropionate; Oestradiol Dipropionate; E2 Dipropionate; NSC 17591; Estra-1,3,5(10)-triene-3,17β-diol 3,17-dipropionate; (17β)-Estra-1,3,5(10)-triene-3,17-diol 3,17-dipropionate
EINECS	204-036-1

Quality Control

Our 17-β-Estradiol 3,17-Dipropionate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) documenting identity, purity, and safety parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.