Description

Metaraminol Bitartrate is a synthetic sympathomimetic amine salt, widely recognized for its potent vasoconstrictor and pressor activity. This high-purity active pharmaceutical ingredient (API) is critical for ensuring reliable and consistent therapeutic performance in critical care formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions developing parenteral solutions for the management of acute hypotensive states and shock.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable formulations for the treatment of hypotension and shock.
• Critical Care Medicine: Formulation of emergency pressor agents used in surgical, intensive care, and emergency room settings.
• Cardiovascular Research: A standard reference compound in pharmacological studies investigating adrenergic receptor activity and vascular tone regulation.
• Veterinary Medicine: Used in veterinary practice for managing hypotension in animals during surgical procedures.
• Analytical Standard: Serves as a high-purity reference standard for quality control and analytical method development in pharmaceutical laboratories.
• Drug Development: A key intermediate or model compound in the research and development of new cardiovascular agents.

Basic Information

Product Name	Metaraminol Bitartrate
CAS No.	33402-03-8
Molecular Formula	C9H13NO2 • C4H6O6
Molecular Weight	317.29 g/mol
Synonyms	Metaraminol Hydrogen Tartrate; L-Metaraminol Bitartrate; (-)-Metaraminol Bitartrate; Aramine Bitartrate; Pressonex Bitartrate; m-Hydroxy-norephedrine Bitartrate; 1-(3-Hydroxyphenyl)-2-amino-1-propanol Bitartrate; L-erythro-1-(3-Hydroxyphenyl)-2-methylaminoethanol Bitartrate
EINECS	251-485-8

Quality Control

Our Metaraminol Bitartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical use, including identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance with cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	-30.0° to -34.0° (c=1 in H2O)
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.