Immunomodulators
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Immunomodulators
Immunomodulators are therapeutic agents designed to modify the activity of the immune system by enhancing, suppressing, or normalizing immune responses. These drugs include cytokines, interferons, interleukins, monoclonal antibodies, small-molecule immune enhancers, and agents that regulate cellular signaling pathways. Immunomodulators are used to treat autoimmune diseases, chronic infections, cancers, allergic disorders, and immune deficiencies. Their mechanisms involve activating immune effector cells, promoting antigen recognition, inhibiting pathogenic immune activation, or restoring immune tolerance. Because immune imbalance can lead to inflammation, tissue damage, or impaired host defense, immunomodulators play a crucial role in restoring physiological homeostasis. Safety considerations include cytokine-release reactions, autoimmune flare-ups, infection risk, and organ toxicity. Immunomodulators remain central to modern precision immunotherapy and disease-modifying treatment strategies.
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