Quinolones

Synthetic Anti-Infective Drugs

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Quinolones

Quinolones are synthetic broad-spectrum antibacterial agents that exert their activity by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. These drugs, including ciprofloxacin, levofloxacin, moxifloxacin, and ofloxacin, demonstrate potent bactericidal effects against Gram-negative organisms and enhanced activity against Gram-positive pathogens in newer generations. Their excellent tissue penetration and oral bioavailability make them widely used for respiratory infections, urinary tract infections, gastrointestinal infections, bone and joint infections, and certain cases of sepsis. However, concerns such as tendinopathy, QT prolongation, CNS effects, and emerging resistance require careful prescribing. Despite these limitations, quinolones remain cornerstone therapeutics in many clinical settings due to their broad spectrum, rapid onset, and versatile dosing options.

Hymoquinolone CAS NO 98267-21-1

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CAS No.:98267-21-1

Grade:Pharmacy Grade

Content:99.90%

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Miraxid CAS NO 98445-47-7

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CAS No.:98445-47-7

Grade:Pharmacy Grade

Content:99.90%

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1-Ethyl-4-Oxo-6,8-Difluoro-7-Piperazino-1,4-Dihydroquinoline-3-Carboxylic Acid CAS NO 99726-76-8

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CAS No.:99726-76-8

Grade:Pharmacy Grade

Content:99.90%

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1-Ethyl-7-[(3S)-3-[(Ethylamino)Methyl]-1-Pyrrolidinyl]-6,8-Difluoro-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid CAS NO 99735-05-4

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CAS No.:99735-05-4

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Content:99.90%

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N,1-Dicyclopropyl-6,7-Difluoro-8-Methoxy-4-Oxoquinoline-3-Carboxamide CAS NO 929962-29-8

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CAS No.:929962-29-8

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Content:99.90%

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Ht-61 CAS NO 936622-80-9

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CAS No.:936622-80-9

Grade:Pharmacy Grade

Content:99.90%

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Butanedioicacid,2-Hydroxy-,Compd.With7-[(3S,5S)-3-Amino-5-Methyl-1-Piperidinyl]-1-Cyclopropyl-1,4-Dihydro-8-Methoxy-4-Oxo-3-Quinolinecarboxylicacid CAS NO 951163-60-3

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CAS No.:951163-60-3

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Content:99.90%

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3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-[2,2,2-trifluoro-1-[(3-Methyl-1-oxobutyl)aMino]-1-(trifluoroMethyl)ethyl]-1-piperazinyl]- CAS NO 196401-21-5

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CAS No.:196401-21-5

Grade:Pharmacy Grade

Content:99.90%

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