Quinolones

Synthetic Anti-Infective Drugs

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Quinolones

Quinolones are synthetic broad-spectrum antibacterial agents that exert their activity by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. These drugs, including ciprofloxacin, levofloxacin, moxifloxacin, and ofloxacin, demonstrate potent bactericidal effects against Gram-negative organisms and enhanced activity against Gram-positive pathogens in newer generations. Their excellent tissue penetration and oral bioavailability make them widely used for respiratory infections, urinary tract infections, gastrointestinal infections, bone and joint infections, and certain cases of sepsis. However, concerns such as tendinopathy, QT prolongation, CNS effects, and emerging resistance require careful prescribing. Despite these limitations, quinolones remain cornerstone therapeutics in many clinical settings due to their broad spectrum, rapid onset, and versatile dosing options.

Ethyl 1-Amino-7-Chloro-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylate CAS NO 88569-30-6

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CAS No.:88569-30-6

Grade:Pharmacy Grade

Content:99.90%

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3-Quinolinecarboxylic Acid, 6-Fluoro-1,4-Dihydro-1-(Methylamino)-7-(4- Methyl-1-Piperazinyl)-4-Oxo-, n-Oxide CAS NO 88569-53-3

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CAS No.:88569-53-3

Grade:Pharmacy Grade

Content:99.90%

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1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-[(4Ar,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-3-Quinolinecarboxylic Acid CAS NO 855661-71-1

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CAS No.:855661-71-1

Grade:Pharmacy Grade

Content:99.90%

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Ciprofloxacin Lactate CAS NO 857213-31-1

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CAS No.:857213-31-1

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Content:99.90%

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Fluorapacin CAS NO 869811-23-4

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CAS No.:869811-23-4

Grade:Pharmacy Grade

Content:99.90%

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3-Quinolinecarboxylic Acid, 7-[(3E)-3-(2-Amino-1-Fluoroethylidene)-1-Piperidinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-4-Oxo- CAS NO 878592-87-1

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CAS No.:878592-87-1

Grade:Pharmacy Grade

Content:99.90%

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Fleroxacinlactate CAS NO 896139-71-2

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CAS No.:896139-71-2

Grade:Pharmacy Grade

Content:99.90%

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Lascufloxacin CAS NO 848416-07-9

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CAS No.:848416-07-9

Grade:Pharmacy Grade

Content:99.90%

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