Quinolones

Synthetic Anti-Infective Drugs

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Quinolones

Quinolones are synthetic broad-spectrum antibacterial agents that exert their activity by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. These drugs, including ciprofloxacin, levofloxacin, moxifloxacin, and ofloxacin, demonstrate potent bactericidal effects against Gram-negative organisms and enhanced activity against Gram-positive pathogens in newer generations. Their excellent tissue penetration and oral bioavailability make them widely used for respiratory infections, urinary tract infections, gastrointestinal infections, bone and joint infections, and certain cases of sepsis. However, concerns such as tendinopathy, QT prolongation, CNS effects, and emerging resistance require careful prescribing. Despite these limitations, quinolones remain cornerstone therapeutics in many clinical settings due to their broad spectrum, rapid onset, and versatile dosing options.

Pipemidic Acid Trihydrate CAS NO 72571-82-5

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CAS No.:72571-82-5

Grade:Pharmacy Grade

Content:99.90%

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Enoxacin CAS NO 74011-58-8

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CAS No.:74011-58-8

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Content:99.90%

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1,8-Naphthyridine-3-Carboxylic Acid, 1,4-Dihydro-1-Ethyl-6-Fluoro-4-Ox o-7-(1-Piperazinyl)-, Monomethanesulfonate CAS NO 75167-06-5

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CAS No.:75167-06-5

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Content:99.90%

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1,8-Naphthyridine-3-Carboxylic Acid, 1,4-Dihydro-1-Ethenyl-6-Fluoro-4- Oxo-7-(1-Piperazinyl)-,Monohydrochloride CAS NO 75167-16-7

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CAS No.:75167-16-7

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Content:99.90%

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1-Ethyl-6,8-Difluoro-1,4-Dihydro-7-(4-Methyl-1-Piperazinyl)-4-Oxo-3-Quinolinecarboxylic Acid CAS NO 75338-41-9

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CAS No.:75338-41-9

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Content:99.90%

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Flosequinoxan CAS NO 76568-68-8

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CAS No.:76568-68-8

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Content:99.90%

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Quinezamide CAS NO 77197-48-9

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CAS No.:77197-48-9

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Content:99.90%

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Esafloxacin CAS NO 79286-77-4

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CAS No.:79286-77-4

Grade:Pharmacy Grade

Content:99.90%

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