Antitubercular and Antileprosy Drugs

Antitubercular and Antileprosy Drugs

Antitubercular and antileprosy drugs target Mycobacterium tuberculosis and Mycobacterium leprae, pathogens characterized by slow growth, lipid-rich cell walls, and intrinsic resistance to many traditional antibiotics. First-line antitubercular drugs-such as isoniazid, rifampicin, pyrazinamide, and ethambutol-act by inhibiting cell wall mycolic acid synthesis, blocking RNA transcription, disrupting membrane energetics, or impairing essential enzyme pathways. Antileprosy agents including dapsone, clofazimine, and rifampicin are used in multidrug therapy to prevent resistance and ensure bacterial eradication. Due to the persistence of mycobacteria in host tissues, long treatment durations are necessary, often extending for six months to two years depending on disease severity and drug susceptibility. These therapies remain fundamental to global tuberculosis and leprosy control programs, although emerging multidrug-resistant strains pose ongoing clinical and public health challenges.

Ethambutol Dihydrochloride CAS NO 1070-11-7

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CAS No.:1070-11-7

Grade:Pharmacy Grade

Content:99.0%

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(N)1-Acetylisoniazid CAS NO 1078-38-2

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CAS No.:1078-38-2

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Content:99.0%

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Etocarlide CAS NO 1234-30-6

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CAS No.:1234-30-6

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Content:99.0%

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Isonicotinic Acid, 1,2-Dihydro-1-Methyl-, Hydrazide (7Ci,8Ci) CAS NO 1452-75-1

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CAS No.:1452-75-1

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Content:99.0%

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Aethoxidum CAS NO 1756-44-1

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CAS No.:1756-44-1

Grade:Pharmacy Grade

Content:99.90%

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L-Ethambutol CAS NO 10054-05-4

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CAS No.:10054-05-4

Grade:Pharmacy Grade

Content:99.90%

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Aconiazide CAS NO 13410-86-1

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CAS No.:13410-86-1

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Content:99.90%

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Methaniazide CAS NO 13447-95-5

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CAS No.:13447-95-5

Grade:Pharmacy Grade

Content:99.90%

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