Description

L-Ethambutol CAS NO 10054-05-4 is a synthetic, bacteriostatic antimycobacterial agent belonging to the ethylenediamine class. It is a critical first-line pharmaceutical active ingredient (API) used in the global fight against tuberculosis. This compound is essential for manufacturers of anti-tuberculosis combination drugs, research institutions, and pharmaceutical companies developing and producing TB treatments worldwide.

Application

• Pharmaceutical API: Primary use as the active pharmaceutical ingredient in fixed-dose combination tablets for the treatment of pulmonary and extrapulmonary tuberculosis.
• Antituberculosis Drug Formulations: A key component in first-line TB regimens, typically combined with isoniazid, rifampicin, and pyrazinamide.
• Research & Development: Used in microbiological and pharmacological research to study Mycobacterium tuberculosis and develop new therapeutic protocols.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical manufacturing and regulatory laboratories.
• Veterinary Medicine: Potential application in the treatment of mycobacterial infections in animals.

Basic Information

Product Name	L-Ethambutol
CAS No.	10054-05-4
Molecular Formula	C10H24N2O2
Molecular Weight	204.31 g/mol
Synonyms	Ethambutol; (+)-Ethambutol; (S,S)-Ethambutol; EMB; Dextro-2,2'-(Ethylenediimino)-di-1-butanol; Myambutol; Etibi; Dadibutol; Dexambutol; Servambutol; Afimocil; (2S,2'S)-2,2'-(Ethane-1,2-diyldiimino)dibutan-1-ol
EINECS	233-162-8

Quality Control

Our L-Ethambutol is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical intermediates and APIs. We offer grades compliant with major pharmacopoeial standards, including USP and EP. Every batch undergoes comprehensive analytical testing, and a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided to guarantee traceability and consistency for your production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.5% - 101.0%
Specific Rotation	+6.0° to +7.0°
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.