Description

N-(5-Oxo-L-Pro-L-Gln-L-Gln-L-Lac-L-Pro-N-methyl-D-Leu-)cyclo[L-Thr*-[(3S,4R)-3-hydroxy-4-[(S)-1-methylpropyl]-γAbu-]-[(2S,4S)-4-hydroxy*-2,5-dimethyl-3-oxohexanoyl]-L-Leu-L-Pro-N,O-dimethyl-L-Tyr-] is a complex, cyclic peptide derivative of significant interest in advanced pharmaceutical research and development. Its intricate structure, featuring multiple non-proteinogenic amino acids and a unique macrocyclic framework, makes it a valuable intermediate or reference standard for exploring novel bioactive compounds. This product is primarily targeted at research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of peptide-based therapeutics and the study of complex molecular interactions.

Application

• Pharmaceutical Research Intermediate: Serves as a key building block or precursor in the synthesis of novel peptide-based drug candidates.
• Reference Standard for Analytical Development: Used for method development, validation, and quality control in HPLC, LC-MS, and other analytical techniques within QC/QA laboratories.
• Biochemical Probe: Utilized in academic and industrial research to study enzyme inhibition, receptor binding, or other specific biological mechanisms.
• Fine Chemical Synthesis: Acts as a specialized starting material for the custom synthesis of complex molecular entities for client-specific projects.
• Peptide Chemistry Studies: Employed in methodological research focused on cyclization techniques, peptide coupling, and the stabilization of peptide structures.

Basic Information

Item	Details
Product Name	N-(5-Oxo-L-Pro-L-Gln-L-Gln-L-Lac-L-Pro-N-methyl-D-Leu-)cyclo[L-Thr*-[(3S,4R)-3-hydroxy-4-[(S)-1-methylpropyl]-γAbu-]-[(2S,4S)-4-hydroxy*-2,5-dimethyl-3-oxohexanoyl]-L-Leu-L-Pro-N,O-dimethyl-L-Tyr-]
CAS No.	97230-31-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cyclic Peptide 97230-31-4; Cyclosporin G Derivative; [Thr2, Leu5, Leu10, Abu11, Nva2]-Cyclosporin A Analog; UNII-9P3N4B8B3T; (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4-hexen-1-yl]-1,4,7,10,12,15,18,21,24,27,30,33-dodecahydro-9,21,24,27,30-pentamethyl-6-(1-methylethyl)-3-(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28-decaoxo-13-(2-propen-1-yl)-1H-azepino[23',24':23,24][1,10,4,7,13,16,19,22]octaoxadiazacyclotetracosin-26-carboxamide (related IUPAC-style name)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, related substances, and other critical parameters are available upon request. We adhere to a cGMP-compliant quality management system to support its use in research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Maximum Impurity	≤ 2.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.