Description

Elamipretide is a synthetic tetrapeptide compound with significant therapeutic potential. It is primarily recognized for its role as a mitochondrial-targeted agent, designed to improve mitochondrial function and cellular energy metabolism. This compound is of critical interest to pharmaceutical researchers and developers working on treatments for diseases linked to mitochondrial dysfunction. Its application is focused within the advanced pharmaceutical sector, particularly in drug discovery and clinical development pipelines.

Application

• Pharmaceutical Active Ingredient (API): Serves as the core active component in investigational drug formulations targeting mitochondrial diseases.
• Preclinical & Clinical Research: Used extensively in laboratory studies and clinical trials to evaluate efficacy in conditions such as Barth syndrome, primary mitochondrial myopathies, and heart failure.
• Mitochondrial Pharmacology: A key tool compound for studying mitochondrial membrane interactions, cardiolipin stabilization, and cellular bioenergetics.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in studies exploring peptide delivery, cellular uptake mechanisms, and the pathophysiology of oxidative stress.

Basic Information

Product Name	Elamipretide
CAS No.	736992-21-5
Molecular Formula	C31H57N7O9
Molecular Weight	671.84 g/mol
Synonyms	SS-31; Bendavia; MTP-131; (2',6'-Dimethyltyrosyl)-D-Arg-Phe-Lys-NH2; D-Arg-2',6'-Dmt-Lys-Phe-NH2; Elamipretide acetate; Szeto-Schiller peptide 31
EINECS	Contact for details

Quality Control

Our Elamipretide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and assay, identity confirmation by mass spectrometry and NMR, and stringent controls for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Single Impurity (HPLC)	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.