Description

1-(4-(1-(2,6-difluorobenzyl)-5-(((2-methoxyethyl)(methyl)amino)methyl)-3-(6-methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-3-methoxyurea is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its role in the research and development of novel therapeutic agents, particularly in targeted disease areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Kinase Inhibitor Research: The thienopyrimidine-dione core structure suggests application in the development of small molecule kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry: Used by medicinal chemists for structure-activity relationship (SAR) studies and lead optimization in drug discovery campaigns.
• Biochemical Research: Employed as a reference standard or a tool compound in biochemical assays to study specific biological pathways and target engagement.
• Custom Synthesis: Supplied for custom synthesis and contract manufacturing of novel chemical entities for pharmaceutical partners.

Basic Information

Product Name	1-(4-(1-(2,6-difluorobenzyl)-5-(((2-methoxyethyl)(methyl)amino)methyl)-3-(6-methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-3-methoxyurea
CAS No.	737789-61-6
Molecular Formula	C31H32F2N6O6S
Molecular Weight	654.69 g/mol
Synonyms	UNII-6J9P6QDK6C; 6J9P6QDK6C; 737789-61-6; Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 1-[(2,6-difluorophenyl)methyl]-6-[4-[(methoxycarbonyl)amino]phenyl]-5-[[[2-methoxyethyl)methylamino]methyl]-3-(6-methoxy-3-pyridazinyl)-; 1-[(2,6-Difluorophenyl)methyl]-6-[4-[(methoxycarbonyl)amino]phenyl]-5-[[[2-methoxyethyl)methylamino]methyl]-3-(6-methoxy-3-pyridazinyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and reliability for critical research applications. Quality is verified through advanced analytical techniques including HPLC, NMR, and LC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.