Description

2-[3-(Acetyloxy)-4-Methoxyphenyl]-5-hydroxy-6-iodo-7-[[2,3,4-tri-O-acetyl-6-O-(2,3,4-tri-O-acetyl-6-deoxy-α-L-Mannopyranosyl)-β-D-glucopyranosyl]oxy]-4H-1-Benzopyran-4-one is a complex, high-purity flavonoid glycoside derivative, serving as a critical advanced intermediate and reference standard for pharmaceutical research and development. Its intricate structure, featuring acetyl-protected sugar moieties and an iodine substituent, makes it invaluable for synthesizing novel bioactive compounds and for analytical method development. This product is primarily targeted at pharmaceutical R&D laboratories, academic research institutions, and biotech companies engaged in drug discovery, particularly in the fields of oncology, metabolic diseases, and inflammation.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel flavonoid-based drug candidates targeting specific biological pathways.
• Analytical Reference Standard: Used for the identification, purity assessment, and quantification in HPLC, LC-MS, and NMR methods during drug development and quality control.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate structure-activity relationships (SAR) of glycosylated flavonoids.
• Process Chemistry Development: Serves as a model compound for optimizing glycosylation, protection, and deprotection reactions in complex molecule synthesis.
• Academic Research: Utilized in university laboratories for advanced studies in organic synthesis, natural product chemistry, and medicinal chemistry.

Basic Information

Item	Details
Product Name	2-[3-(Acetyloxy)-4-Methoxyphenyl]-5-hydroxy-6-iodo-7-[[2,3,4-tri-O-acetyl-6-O-(2,3,4-tri-O-acetyl-6-deoxy-α-L-Mannopyranosyl)-β-D-glucopyranosyl]oxy]-4H-1-Benzopyran-4-one
CAS No.	705974-42-1
Molecular Formula	C46H47IO22
Molecular Weight	1102.76 g/mol
Synonyms	6-Iodo-7-[[2,3,4-tri-O-acetyl-6-O-(2,3,4-tri-O-acetyl-6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-acetoxy-4-methoxyphenyl)-4H-chromen-4-one; Acetylated Iodoflavonoid Glycoside; Peracetylated Iodinated Flavone Glycoside; 7-O-[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]-5-hydroxy-6-iodo-2-(3-acetoxy-4-methoxyphenyl)-4H-1-benzopyran-4-one, 2',3,3',4',6,6'-hendecaacetate; CAS 705974-42-1.
EINECS	Contact for details

Quality Control

Every batch of this high-purity intermediate is manufactured and tested under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles to ensure it meets the exacting standards required for pharmaceutical research. Our quality protocols are designed to support GMP-compliant development workflows, ensuring traceability and data integrity for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.