Description

(Z)-2-Methyl-2-butenoic acid [(3aS,4S,5R,6R,8Z,10R,11aR)-4-acetoxy-2,3,3a,4,5,6,7,10,11,11a-decahydro-6-hydroxy-6,10-dimethyl-3-methylene-2,7-dioxocyclodeca[b]furan-5-yl] ester is a high-purity, complex sesquiterpene lactone derivative, valued for its role as a key synthetic intermediate and reference standard in advanced organic chemistry. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized in pharmaceutical R&D, agrochemical synthesis, and academic research focused on natural product chemistry and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of complex drug candidates, particularly in oncology and anti-inflammatory research.
• Reference Standard: Used as an analytical standard in HPLC, LC-MS, and NMR for quality control, method development, and impurity profiling in related chemical processes.
• Natural Product Synthesis: Acts as a key intermediate in the total or semi-synthesis of complex natural products and their analogs for biological evaluation.
• Agrochemical Research: Employed in the discovery and development of new active ingredients with potential herbicidal or insecticidal properties.
• Medicinal Chemistry: Provides a structurally complex core for structure-activity relationship (SAR) studies and the generation of novel chemical libraries.
• Biochemical Research: Used as a probe or substrate in enzymatic studies and for investigating specific biological pathways.

Basic Information

Product Name	(Z)-2-Methyl-2-butenoic acid [(3aS,4S,5R,6R,8Z,10R,11aR)-4-acetoxy-2,3,3a,4,5,6,7,10,11,11a-decahydro-6-hydroxy-6,10-dimethyl-3-methylene-2,7-dioxocyclodeca[b]furan-5-yl] ester
CAS No.	63194-23-0
Molecular Formula	C22H30O7
Molecular Weight	406.47 g/mol
Synonyms	Alantolactone 4-acetate tiglate; Isoalantolactone 4-acetate tiglate; (3aS,4S,5R,6R,8Z,10R,11aR)-5-[(2Z)-2-Methylbut-2-enoyl]oxy-4-acetoxy-6,10-dimethyl-3-methylidene-2,7-dioxo-1,3a,4,5,6,7,10,11a-octahydrocyclodeca[b]furan-6-yl acetate; 4-Acetoxyisoalantolactone tiglate; Tiglic acid ester of 4-acetoxyisoalantolactone; 4-Acetoxyalantolactone tiglate; Sesquiterpene lactone derivative 63194-23-0
EINECS	Contact for details

Quality Control

Our (Z)-2-Methyl-2-butenoic acid [(3aS,4S,5R,6R,8Z,10R,11aR)-4-acetoxy-2,3,3a,4,5,6,7,10,11,11a-decahydro-6-hydroxy-6,10-dimethyl-3-methylene-2,7-dioxocyclodeca[b]furan-5-yl] ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.