Description

Costunolide is a high-purity sesquiterpene lactone compound, recognized for its significant biological and pharmacological activities. This versatile intermediate is crucial for research and development in advanced therapeutic and cosmetic formulations. It is primarily sought by the pharmaceutical, nutraceutical, and high-end cosmetic industries for its role as a key building block in anti-inflammatory and anticancer research.

Application

• Pharmaceutical Intermediate: Serves as a critical starting material or reference standard in the synthesis of novel anti-inflammatory and chemopreventive drug candidates.
• Natural Product Research: Used as a standard compound in academic and industrial laboratories for studying sesquiterpene lactone biosynthesis, metabolism, and bioactivity.
• Cosmetic Actives: Incorporated into advanced skincare formulations for its potential anti-aging and skin-soothing properties derived from its biological profile.
• Nutraceutical Development: Explored as a bioactive component in dietary supplements targeting wellness and inflammatory pathways.
• Agricultural Chemistry: Investigated for its natural pesticidal or plant growth regulation properties in the development of bio-based agrochemicals.
• Flavor & Fragrance: Used in trace amounts to create complex, woody, and balsamic notes in premium fragrance compositions.

Basic Information

Product Name	Costunolide
CAS No.	553-21-9
Molecular Formula	C15H20O2
Molecular Weight	232.32 g/mol
Synonyms	Costunolide; (-)-Costunolide; (3aR,6aR,9aS,9bR)-6a,9-Dimethyl-3-methylidene-2-oxo-2,3,3a,4,5,6,9a,9b-octahydroazuleno[4,5-b]furan; Saussurea lactone; VL-1107; Parthenolide isomer
EINECS	209-041-9

Quality Control

Our Costunolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets stringent specifications for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	103°C - 107°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.