Description

Illudin M is a potent, naturally occurring sesquiterpene compound derived from certain fungi, including the Jack O'Lantern mushroom (*Omphalotus illudens*). This molecule serves as a critical pharmacological tool and research chemical due to its unique biological activity, primarily its ability to form DNA adducts and inhibit RNA synthesis. It is essential for academic and pharmaceutical researchers focused on oncology, molecular biology, and the development of novel cytotoxic agents or antibody-drug conjugates (ADCs).

Application

• Biomedical Research: As a reference standard and active agent in studies investigating DNA damage, cytotoxicity, and mechanisms of cell death.
• Oncology Drug Discovery: Serves as a lead compound or warhead for the development of novel chemotherapeutic agents and targeted cancer therapies.
• Antibody-Drug Conjugate (ADC) Development: Used in research to create and evaluate potent cytotoxic payloads linked to targeting antibodies.
• Biochemical Assays: Employed as a tool compound to study transcription inhibition and to validate related biochemical pathways in vitro.
• Toxicology Studies: Utilized to understand the toxicological profile of illudin-class compounds and their metabolic activation.
• Natural Product Chemistry: Acts as a benchmark for the isolation, characterization, and synthesis of complex fungal metabolites.

Basic Information

Product Name	Illudin M
CAS No.	1146-04-9
Molecular Formula	C15H20O4
Molecular Weight	264.32 g/mol
Synonyms	6-Hydroxymethyl-4,4a,5,6,7,8-hexahydro-4a,7-dimethylcyclopenta[g]isobenzofuran-1(3H)-one; Illudin M; 6-(Hydroxymethyl)-2,3,3a,7a-tetrahydro-3a,6-dimethyl-1-benzofuran-4,7-dione; Lampterol
EINECS	Contact for details

Quality Control

Our Illudin M is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, store at 2-8°C. Allow the container to reach room temperature before opening to prevent condensation. Keep away from oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.