Description

[1R,(-)]-1,2,3,4,4Aα,5,6,8Aβ-Octahydro-7-Methyl-4-Methylene-1-Isopropylnaphthalene is a high-purity, stereochemically defined sesquiterpene derivative that serves as a critical chiral intermediate and reference standard in advanced organic synthesis. Its precise molecular architecture makes it invaluable for research and development in the fine chemical and pharmaceutical sectors, where stereochemical control is paramount. This compound is essential for chemists and manufacturers developing complex molecules, including fragrances, flavors, and active pharmaceutical ingredients (APIs) requiring specific isomeric purity.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Used in the research and production of complex drug molecules where the specific stereochemistry is crucial for biological activity.
• Fragrance and Flavor Ingredient Precursor: Serves as a key building block for synthesizing high-value aromatic compounds with woody, amber, or musk notes.
• Reference Standard for Analytical Chemistry: Provides a certified material for method development, calibration, and quality control in chromatographic analysis (GC, HPLC).
• Academic and Industrial R&D: Employed in organic chemistry research to study terpene transformations, cyclization reactions, and asymmetric synthesis methodologies.
• Synthesis of Natural Product Analogs: Acts as a starting material for the semi-synthesis of natural products and their derivatives for biological screening.
• Specialty Chemical Manufacturing: Used in the production of advanced materials, ligands for catalysis, and other high-value specialty chemicals.

Basic Information

Product Name	[1R,(-)]-1,2,3,4,4Aα,5,6,8Aβ-Octahydro-7-Methyl-4-Methylene-1-Isopropylnaphthalene
CAS No.	1460-97-5
Molecular Formula	C15H24
Molecular Weight	204.35 g/mol
Synonyms	(-)-Isolongifolene; (1R)-1,2,3,4,4a,5,6,8a-Octahydro-7-methyl-4-methylene-1-(1-methylethyl)naphthalene; (1R)-Isolongifolene; 1R-Isolongifolene; [1R-(-)]-Isolongifolene; α-Isolongifolene; NSC 146006; 1-Isopropyl-7-methyl-4-methylene-1,2,3,4,4a,5,6,8a-octahydronaphthalene
EINECS	Contact for details

Quality Control

Our [1R,(-)]-Isolongifolene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is subjected to comprehensive analytical testing, including chiral purity assessment by GC or HPLC, to confirm identity and isomeric composition. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, optical rotation, and impurity profile. We support custom synthesis and can tailor specifications, including enantiomeric excess (ee), to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 97.0%
Chiral Purity (GC/HPLC)	≥ 98.0% ee ([1R]-isomer)
Optical Rotation [α]20/D	Contact for details
Refractive Index n20/D	Contact for details
Specific Gravity	Contact for details
Related Substances (GC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.