Description

2-PYRROLIDINECARBOXAMIDE, N-[3-[[4-(AMINOIMINOMETHYL)BENZOYL]AMINO]PROPYL]-1-[[2,4-DICHLORO-3-[[(2,4-DIMETHYL-8-QUINOLINYL)OXY]METHYL]PHENYL]SULFONYL]-, (2S)-, MONOMETHANESULFONATE is a high-purity, non-peptidic small molecule compound designed for advanced research and development. This specialized chemical serves as a potent and selective inhibitor of specific proteolytic enzymes, making it a critical tool for investigating disease pathways. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on oncology, inflammation, and metabolic disorders.

Application

• Pharmaceutical Research & Development: As a key intermediate or active pharmaceutical ingredient (API) in preclinical studies for novel therapeutics.
• Protease Inhibition Studies: Used in biochemical assays to study the function and inhibition of specific serine or cysteine proteases.
• Oncology Research: Investigation of tumor growth, metastasis, and angiogenesis pathways where target proteases are implicated.
• Inflammatory Disease Models: Research into conditions like arthritis, where protease activity plays a significant role in tissue remodeling.
• Biochemical Tool Compound: Serves as a selective probe to validate drug targets and understand enzyme kinetics in complex biological systems.
• High-Throughput Screening (HTS): Used as a reference standard or control compound in drug discovery campaigns.

Basic Information

Product Name	2-PYRROLIDINECARBOXAMIDE, N-[3-[[4-(AMINOIMINOMETHYL)BENZOYL]AMINO]PROPYL]-1-[[2,4-DICHLORO-3-[[(2,4-DIMETHYL-8-QUINOLINYL)OXY]METHYL]PHENYL]SULFONYL]-, (2S)-, MONOMETHANESULFONATE
CAS No.	515880-69-0
Molecular Formula	C₃₄H₄₀Cl₂N₆O₆S₂
Molecular Weight	779.75 g/mol
Synonyms	UNII-2JX8404W5A; (2S)-N-[3-[[4-(Carbamimidoyl)benzoyl]amino]propyl]-1-[[2,4-dichloro-3-[[(2,4-dimethyl-8-quinolyl)oxy]methyl]phenyl]sulfonyl]pyrrolidine-2-carboxamide methanesulfonate; Protease Inhibitor 515880-69-0; 2-Pyrrolidinecarboxamide methanesulfonate salt derivative; N-{3-[(4-Carbamimidoylbenzoyl)amino]propyl}-1-{[2,4-dichloro-3-({[(2,4-dimethylquinolin-8-yl)oxy]methyl})phenyl]sulfonyl}-L-prolinamide methanesulfonate
EINECS	Contact for details

Quality Control

Our production of this advanced research chemical adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.