Description

(2S,1S,3'R,4'bS,8'aS,9'S,10'S)-3',10'-Diacetoxy-4'b,5',6',8'a,9',10'-hexahydro-9'-hydroxy-2,4'b,7',8'-tetramethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione is a complex, high-purity steroidal derivative with a unique spirocyclic structure. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It serves as a critical chiral intermediate or reference standard for researchers in medicinal chemistry, process development, and analytical laboratories.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel steroidal drugs and bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Process Chemistry Development: Serves as a reference material for developing and scaling up synthetic routes for complex organic molecules.
• Analytical Reference Standard: Employed as a high-purity standard for method development, validation, and quality control (HPLC, GC, LC-MS) in analytical laboratories.
• Academic & Institutional Research: Used in universities and research institutes for studying stereochemistry, reaction mechanisms, and natural product synthesis.
• Biochemical Probe Development: Potential use in developing probes to study steroid hormone receptors or related biological pathways.

Basic Information

Product Name	(2S,1S,3'R,4'bS,8'aS,9'S,10'S)-3',10'-Diacetoxy-4'b,5',6',8'a,9',10'-hexahydro-9'-hydroxy-2,4'b,7',8'-tetramethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione
CAS No.	56197-50-3
Molecular Formula	C26H34O7
Molecular Weight	458.55 g/mol
Synonyms	9'-Hydroxy-3',10'-diacetoxy-2,4'b,7',8'-tetramethyl-1',2',3',4',4'a,4'b,5',6',8'a,9',10',10'a-dodecahydrospiro[cyclopropane-1,2'-phenanthrene]-1',4'-dione; 3',10'-Di-O-acetyl derivative of a tetrahydroxylated spirocyclopropylphenanthrenedione; Spiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione derivative; CAS 56197-50-3; A complex steroidal spiroketone diacetate.
EINECS	Contact for details

Quality Control

Our (2S,1S,3'R,4'bS,8'aS,9'S,10'S)-3',10'-Diacetoxy-4'b,5',6',8'a,9',10'-hexahydro-9'-hydroxy-2,4'b,7',8'-tetramethylspiro[cyclopropane-1,2'(1'H)-phenanthrene]-1',4'(3'H)-dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis, and structural confirmation via NMR and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de (by Chiral HPLC)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.