Description

20-β-Dihydrocortisol is a key synthetic corticosteroid intermediate with significant pharmaceutical relevance. This compound is valued for its role in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development and production of anti-inflammatory and immunosuppressive medications.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent corticosteroid drugs.
• Research & Development: Used in biochemical research to study steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• API Synthesis: Integral to the manufacturing process of various therapeutic steroids targeting inflammation and autoimmune disorders.

Basic Information

Product Name	20-β-Dihydrocortisol
CAS No.	116-58-5
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	20β-Dihydrocortisol; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione; 20β-Hydroxycortisol; 20β-DHC; (11β)-11,17,21-Trihydroxypregn-4-ene-3,20-dione; Cortisol 20β-reduced; 20β-Reduced cortisol
EINECS	204-149-7

Quality Control

Our 20-β-Dihydrocortisol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.