Description

4-Pregnen-20-β-Ol-3-One is a high-purity steroid intermediate, also known as 20β-Hydroxypregn-4-en-3-one. This compound is a critical building block in the synthesis of various pharmaceutical steroids and hormones, valued for its defined stereochemistry at the C-20 position. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of corticosteroids, progestogens, and other therapeutic steroid hormones.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development, validation, and impurity profiling.
• Biochemical Research: Employed in metabolic pathway studies and enzymatic conversion research related to steroidogenesis.
• Process Development: Serves as a starting material or intermediate for process chemists developing scalable and efficient synthetic routes.

Basic Information

Product Name	4-Pregnen-20-β-Ol-3-One
CAS No.	145-15-3
Molecular Formula	C21H32O2
Molecular Weight	316.48 g/mol
Synonyms	20β-Hydroxypregn-4-en-3-one; 20β-Hydroxy-4-pregnen-3-one; 20β-Dihydroprogesterone; 20β-OH-P4; Pregn-4-ene-3,20-diol, (20β)-; NSC 10483; 20β-Hydroxyprogesterone
EINECS	205-647-9

Quality Control

Our 4-Pregnen-20-β-Ol-3-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.