Description

(1S,3R,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-1,3-diol is a high-purity steroidal diol compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmaceutical intermediate and reference standard for the synthesis and analysis of complex steroid-based therapeutics. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of hormone therapies, anti-inflammatory agents, and other specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC) of steroid products via HPLC, GC-MS, or NMR.
• Biochemical Research: Employed in academic and industrial R&D to study steroid receptor interactions, metabolic pathways, and structure-activity relationships (SAR).
• Process Development: Serves as a starting material or intermediate for optimizing scalable synthetic routes under GMP conditions.
• Custom Synthesis: A precursor for the preparation of novel steroid derivatives with potential therapeutic applications.

Basic Information

Item	Details
Product Name	(1S,3R,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-1,3-diol
CAS No.	50392-32-0
Molecular Formula	C27H46O3
Molecular Weight	418.66 g/mol
Synonyms	17-(6-Hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-1,3-diol; (22R)-22-Hydroxy-22-methyl-24-norchol-5-ene-3β,7α-diol; 3β,7α-Dihydroxy-22-methyl-22-hydroxy-24-norchol-5-ene; Steroidal Diol Derivative; 24-Norcholene Diol Derivative; 50392-32-0; Cholestane Diol Intermediate
EINECS	Contact for details

Quality Control

Our production of this steroidal intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical research and development applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC-MS, and 1H/13C NMR for identity confirmation and purity assessment. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key specifications such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.