Description

(5R,5aα)-5,8,8aβ,9α-Tetrahydro-9β-[(4-O,6-O-[(2-thienyl)methylene]-β-D-glucopyranosyl)oxy]-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one is a complex, high-purity organic compound featuring a unique fused-ring structure with a glucopyranosyl moiety. This compound is of significant interest as a specialized intermediate or reference standard in advanced pharmaceutical research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, particularly in oncology and antiviral research.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Medicinal Chemistry Research: A valuable tool for structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Research: Potential use as a probe or inhibitor in studying specific enzymatic or cellular pathways.
• Process Development: Employed in scaling up synthetic routes for pilot and commercial-scale production of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting point for the preparation of novel analogs and derivatives for proprietary research.

Basic Information

Product Name	(5R,5aα)-5,8,8aβ,9α-Tetrahydro-9β-[(4-O,6-O-[(2-thienyl)methylene]-β-D-glucopyranosyl)oxy]-5β-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
CAS No.	35317-31-8
Molecular Formula	C₃₆H₃₄O₁₄S
Molecular Weight	698.72 g/mol
Synonyms	Podophyllotoxin 4-O,6-O-(2-thienylmethylene)-β-D-glucopyranoside; 4-O,6-O-[(2-Thienyl)methylene]-β-D-glucopyranosyl podophyllotoxin; 4-O,6-O-(2-Thienylmethylidene)-β-D-glucopyranosyl podophyllotoxin; NSC 330500; 4,6-O-(2-Thienylmethylene)podophyllotoxin β-D-glucoside; 4,6-O-(2-Thienylmethylidene)podophyllotoxin β-D-glucoside; Podophyllotoxin 4,6-O-(2-thienylmethylene)-β-D-glucopyranoside
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under an inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.