Description

Aurovertin is a potent secondary metabolite and polyketide-derived natural product. This compound is of significant interest in biochemical research due to its specific inhibitory activity against mitochondrial ATP synthase, making it a valuable tool for studying cellular energy metabolism and oxidative phosphorylation. It is primarily utilized by research institutions and pharmaceutical development laboratories engaged in enzymology, metabolic pathway analysis, and the discovery of novel bio-active compounds.

Application

• Biochemical Research: A key tool compound for the study of mitochondrial function, specifically as an inhibitor of F1F0-ATP synthase.
• Enzymology Studies: Used to investigate the mechanism and kinetics of ATP synthesis and hydrolysis in purified enzyme preparations and cellular systems.
• Metabolic Pathway Analysis: Employed in cell biology to dissect the role of oxidative phosphorylation in energy production and to study metabolic shifts.
• Pharmaceutical Discovery: Serves as a reference standard and a starting point for the development of novel therapeutic agents targeting energy metabolism in diseases like cancer or microbial infections.
• Academic Research: Used in university and institutional labs for fundamental research in bioenergetics and molecular biology.

Basic Information

Product Name	Aurovertin
CAS No.	11002-90-7
Molecular Formula	C25H34O9
Molecular Weight	478.53 g/mol
Synonyms	Aurovertin B; Antibiotic A 130A; NSC 122040; 6H-2-Benzopyran-6-one, 3,4,4a,5,6,7,8,9-octahydro-4a,9-dihydroxy-3-[(1E)-1-hydroxy-3-methyl-1-buten-1-yl]-4,7,9-trimethyl-2-oxo-, (3R,4S,4aR,9S)-; ATPase inhibitor aurovertin
EINECS	Contact for details

Quality Control

Our Aurovertin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Yellow to pale brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.