Description

Phytosphingosine is a naturally occurring sphingoid base, a fundamental building block for ceramides and other complex sphingolipids essential for skin barrier function and cellular signaling. Its unique structure provides superior stability and skin compatibility compared to synthetic alternatives, making it a premium active ingredient for high-performance formulations. This compound is in high demand within the cosmetic, pharmaceutical, and advanced biomedical research sectors for its proven efficacy in skin repair, anti-aging, and as a bioactive intermediate.

Application

• Cosmetic & Skincare Actives: A key raw material for synthesizing phytoceramides and pseudoceramides used in moisturizers, anti-aging serums, and barrier repair creams.
• Pharmaceutical Intermediates: Serves as a critical chiral building block in the synthesis of novel sphingolipid-based drugs and therapeutic agents.
• Biomedical Research: Used as a standard and reagent in lipidomics research, cell signaling studies, and apoptosis (programmed cell death) investigations.
• Hair Care Formulations: Incorporated into shampoos and conditioners to improve scalp health and strengthen hair fibers by mimicking natural lipids.
• Advanced Delivery Systems: Utilized in the development of lipid nanoparticles (LNPs) and other nanocarriers for targeted drug and cosmetic ingredient delivery.

Basic Information

Product Name	Phytosphingosine
CAS No.	554-62-1
Molecular Formula	C18H39NO3
Molecular Weight	317.51 g/mol
Synonyms	D-ribo-Phytosphingosine; (2S,3S,4R)-2-Amino-1,3,4-octadecanetriol; 4-Hydroxysphinganine; D-erythro-Phytosphingosine; Phytosphingosine HCl; PS; 4-Hydroxy-D-erythro-sphinganine; 4-Hydroxysphingosine
EINECS	209-081-2

Quality Control

Our Phytosphingosine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with relevant standards for cosmetic and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation and hygroscopic nature. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: +4.0° to +6.0° (c=1 in CHCl3)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.