Description

(S)-2,2μ-Diamino-6,6μ-dimethylbiphenyl, (S)-6,6μ-Dimethyl-2,2μ-diaminobiphenyl, (S)-6,6μ-Dimethyl-1,1μ-biphenyl-2,2μ-diamine, (S)-6,6μ-Dimethyl-1,1μ-biphenyl-2,2μ-diyldiamine is a high-value, chiral biphenyl diamine derivative that serves as a critical building block in asymmetric synthesis. Its rigid, axially chiral structure makes it an indispensable ligand and precursor for constructing complex molecular architectures with high enantioselectivity. This compound is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Chiral Ligand in Asymmetric Catalysis: Employed as a precursor for synthesizing privileged ligand frameworks (e.g., BINOL, BINAM derivatives) used in enantioselective hydrogenation, C-C bond formation, and other catalytic transformations.
• Pharmaceutical Intermediate: A key starting material for the synthesis of chiral active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring high stereochemical purity.
• Agrochemical Synthesis: Used in the development of enantiomerically pure herbicides, fungicides, and pesticides, where the specific stereochemistry can significantly influence biological activity and environmental safety.
• Advanced Material Precursor: Serves as a monomer or cross-linker for creating chiral polymers, liquid crystals, and metal-organic frameworks (MOFs) with specialized optical or electronic properties.
• Resolution Agent: Utilized as a chiral selector or resolving agent for the separation of racemic mixtures of acids or other compounds via diastereomeric salt formation.
• Research & Development: A valuable tool compound in academic and industrial research laboratories for exploring new methodologies in stereochemistry and organometallic chemistry.

Basic Information

Item	Details
Product Name	(S)-2,2μ-Diamino-6,6μ-dimethylbiphenyl
CAS No.	3685-05-0
Molecular Formula	C14H16N2
Molecular Weight	212.29 g/mol
Synonyms	(S)-6,6μ-Dimethyl-2,2μ-diaminobiphenyl; (S)-6,6μ-Dimethyl-1,1μ-biphenyl-2,2μ-diamine; (S)-6,6μ-Dimethyl-1,1μ-biphenyl-2,2μ-diyldiamine; (S)-2,2'-Diamino-6,6'-dimethylbiphenyl; (S)-6,6'-Dimethyl-[1,1'-biphenyl]-2,2'-diamine; (S)-BINAM Derivative; (S)-Axially Chiral Diamine; (S)-DMBPDA
EINECS	Contact for details

Quality Control

Our production of (S)-2,2μ-Diamino-6,6μ-dimethylbiphenyl adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including Chiral HPLC, NMR, and specific rotation measurement to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and scale-up projects with custom synthesis and purity grades tailored to specific application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; allow the container to reach ambient temperature before opening to minimize moisture condensation and oxidative degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.