Description

(1R,2R,4R)-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid is a high-purity, chiral bicyclic compound that serves as a versatile and valuable building block in advanced organic synthesis. Its rigid, three-dimensional structure and defined stereochemistry make it an essential precursor for developing complex molecules with specific spatial orientations. This compound is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and material science sectors for applications in asymmetric catalysis, ligand design, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in developing central nervous system (CNS) agents and antiviral compounds.
• Asymmetric Catalyst & Ligand Precursor: Used to construct sophisticated chiral ligands and organocatalysts for enantioselective synthesis, enhancing the efficiency of producing single-isomer products.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science & Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with unique thermal and mechanical properties.
• Academic & Industrial R&D: A fundamental tool in methodological organic chemistry research for studying cycloaddition reactions and stereochemical outcomes.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex terpenoid-like aroma molecules.

Basic Information

Product Name	(1R,2R,4R)-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid
CAS No.	1195-12-6
Molecular Formula	C8H10O2
Molecular Weight	138.16 g/mol
Synonyms	(1R,2R,4R)-5-Norbornene-2-carboxylic Acid; endo-(1R,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic Acid; (1R,2R,4R)-Norborn-5-ene-2-carboxylic Acid; (1R,2R,4R)-2-Carboxynorborn-5-ene; endo-(+)-5-Norbornene-2-carboxylic Acid; (1R,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic Acid; (1R,2R,4R)-2-Norbornene-5-carboxylic Acid
EINECS	214-800-5

Quality Control

Our (1R,2R,4R)-Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.