Description

8-Bromo-2,3,4,5-tetrahydro-1H-benzo[c]azepine is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure makes it a critical intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process R&D teams working on central nervous system (CNS) agents and other bioactive scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel therapeutic agents, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probes: Used in the development of molecular probes and tools for studying biological pathways and protein interactions.
• Agrochemical Synthesis: Intermediate for creating advanced crop protection agents and pesticides with novel modes of action.
• Material Science Research: Building block for synthesizing specialized organic materials and ligands for catalytic systems.

Basic Information

Product Name	8-Bromo-2,3,4,5-tetrahydro-1H-benzo[c]azepine
CAS No.	223915-77-3
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	8-Bromo-2,3,4,5-tetrahydro-1H-3-benzazepine; 1H-Benzo[c]azepine, 8-bromo-2,3,4,5-tetrahydro-; 8-Bromo-1,2,3,5-tetrahydro-4H-3-benzazepin-4-one (keto form); 8-Bromo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ol (tautomer); 8-Bromotetrahydro-3-benzazepine; 223915-77-3; 8-Bromo-THBA
EINECS	Contact for details

Quality Control

Our 8-Bromo-2,3,4,5-tetrahydro-1H-benzo[c]azepine is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each batch to ensure traceability and consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.