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Bicyclo[2.2.1]Heptane, 2,7-Dichloro-, (1R,2S,4S,7S)-Rel- (9Ci) CAS NO 52134-25-5
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CAS No.:52134-25-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Bicyclo[2.2.1]Heptane, 2,7-Dichloro-, (1R,2S,4S,7S)-Rel- (9Ci) is a highly specific stereoisomer of a chlorinated norbornane derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its defined stereochemistry and rigid bicyclic framework make it invaluable for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.
Application
- Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
- Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where its structural rigidity can contribute to biological activity and environmental stability.
- Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity.
- Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with unique thermal or mechanical properties.
- Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including cycloaddition reactions and stereochemistry investigations.
- Flavor & Fragrance Industry: Potential intermediate for synthesizing complex, stereochemically defined odorants and flavor compounds.
Basic Information
| Item | Details |
|---|---|
| Product Name | Bicyclo[2.2.1]Heptane, 2,7-Dichloro-, (1R,2S,4S,7S)-Rel- (9Ci) |
| CAS No. | 52134-25-5 |
| Molecular Formula | C7H10Cl2 |
| Molecular Weight | 165.06 g/mol |
| Synonyms | (1R,2S,4S,7S)-2,7-Dichloronorbornane; rel-(1R,2S,4S,7S)-2,7-Dichlorobicyclo[2.2.1]heptane; 2,7-Dichloronorbornane (specific stereoisomer); endo,endo-2,7-Dichloronorbornane; NSC 406916; Bicyclo[2.2.1]heptane, 2,7-dichloro-, (1R,2S,4S,7S)-rel- |
| EINECS | Contact for details |
Quality Control
Every batch of Bicyclo[2.2.1]Heptane, 2,7-Dichloro-, (1R,2S,4S,7S)-Rel- (9Ci) is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and isomeric purity essential for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Chiral Purity (Chiral HPLC) | ≥ 98.0% ee |
| Melting Point | Contact for details |
| Heavy Metals | < 20 ppm |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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