Description

Benzamide, N-[1-[[[6-cyano-5-(trifluoromethyl)-3-pyridinyl]amino]carbonyl]cyclobutyl]-4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-[3-fluoro-4-[(methylamino)carbonyl]phenyl]- is a sophisticated, high-purity organic compound designed for advanced research and development. This molecule is of significant interest for its potential as a key intermediate or active component in the discovery of novel therapeutics. It is primarily targeted at the pharmaceutical and biotechnology sectors, where complex heterocyclic structures are essential for probing new biological pathways. The compound's unique spirocyclic and multi-fluorinated architecture makes it a valuable building block for medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and targeted therapy research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its complex, multi-functional molecular scaffold.
• Biochemical Probe Development: Employed in the design and synthesis of chemical probes for studying enzyme inhibition and protein-ligand interactions.
• Contract Research & Development (CRO): Supplied to CROs and academic institutions for cutting-edge life science research and custom synthesis projects.
• High-Throughput Screening Libraries: Incorporated into specialized compound libraries for screening against novel biological targets.
• Process Chemistry Development: Used in the development and scale-up of synthetic routes for potential active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Benzamide, N-[1-[[[6-cyano-5-(trifluoromethyl)-3-pyridinyl]amino]carbonyl]cyclobutyl]-4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-[3-fluoro-4-[(methylamino)carbonyl]phenyl]-
CAS No.	2894796-77-9
Molecular Formula	C36H22F8N8O4S
Molecular Weight	814.67 g/mol
Synonyms	N-[1-[[[6-Cyano-5-(trifluoromethyl)-3-pyridinyl]amino]carbonyl]cyclobutyl]-4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-[3-fluoro-4-[(methylamino)carbonyl]phenyl]benzamide; CAS 2894796-77-9; 2-Fluoro-N-[3-fluoro-4-(methylcarbamoyl)phenyl]-4-[7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-N-[1-[[[6-cyano-5-(trifluoromethyl)pyridin-3-yl]carbamoyl]cyclobutyl]benzamide; Spirocyclic Benzamide Derivative; Advanced Pharmaceutical Intermediate 2894796-77-9.
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and analyzed under strict quality management systems. We employ advanced analytical techniques including HPLC, LC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications for assay, purity, and related substances. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. For long-term storage, consider storing at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.