Description

Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, compd. with 4-methylbenzenesulfonate (1:1) is a high-purity, non-racemic pharmaceutical intermediate of significant interest in modern drug discovery. This compound matters as a sophisticated chiral building block, enabling the synthesis of targeted therapeutic agents with specific stereochemical configurations. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel small-molecule drugs, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Synthesis of Biologically Active Compounds: Serves as a core scaffold for creating molecules with potential activity against various disease targets.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential clinical candidates.
• Contract Research & Manufacturing (CRMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and methodology development.

Basic Information

Item	Detail
Product Name	Ethanediamide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-, compd. with 4-methylbenzenesulfonate (1:1)
CAS No.	2605225-71-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N1-(5-Chloro-2-pyridinyl)-N2-[(1R,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide 4-methylbenzenesulfonate; (1R,2R,4S)-N1-(5-Chloro-2-pyridinyl)-N2-(4-(dimethylcarbamoyl)-2-((4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)formamido)cyclohexyl)oxalamide p-toluenesulfonate; Chiral Oxalamide Derivative Tosylate Salt; Advanced Pharmaceutical Intermediate 2605225-71-4
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical research materials. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing specific results for chiral purity, assay, and related substances are available upon request. Our quality management system supports traceability and consistency for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.