Description

2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)- is a sophisticated, high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound is designed for applications requiring precise molecular architecture, offering a unique scaffold for the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of new drug candidates, particularly in areas targeting specific enzyme inhibition or receptor modulation.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development of novel protease inhibitors due to its specific pyrrolidinecarboxamide core structure.
• Bioconjugation & Linker Chemistry: The extended PEG-like chain terminated with a chlorohexyl group makes it suitable for conjugation studies and as a linker in antibody-drug conjugates (ADCs) or prodrug design.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation.

Basic Information

Item	Details
Product Name	2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)-
CAS No.	1799506-07-2
Molecular Formula	C44H55ClN4O8S
Molecular Weight	843.44 g/mol
Synonyms	N-[[2-[2-[2-[2-[(6-Chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-2-oxo-1H-isoindol-2-yl)-3-methylbutanoyl]-4-hydroxy-L-prolinamide; (2S,4R)-1-[(2S)-2-(1,3-Dihydro-2-oxo-1H-isoindol-2-yl)-3-methylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)-2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]phenyl]methyl]pyrrolidine-2-carboxamide; 1799506-07-2; Advanced Pharmaceutical Intermediate; Chloro-PEG4-Thiazole-Phenyl-Pyrrolidinecarboxamide Derivative.
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarboxamide derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet the specific requirements of your research or development program.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.