Description

1-(2-((1R,3S,5R)-3-((2-fluoro-3-(trifluoromethoxy)phenyl)carbamoyl)-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)-5-methyl-1H-pyrazolo[3,4-c]pyridine-3-carboxamide benzoate is a high-purity, complex organic compound designed for advanced research and development applications. This molecule is of significant interest in the pharmaceutical industry due to its intricate structure, which incorporates a fused pyrazolopyridine core linked to a functionalized azabicyclohexane system. It serves as a critical pharmaceutical intermediate or reference standard for drug discovery programs targeting novel therapeutic pathways. This product is essential for researchers and manufacturers in medicinal chemistry and process development who require reliable access to well-characterized building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or metabolic disorder targets.
• Medicinal Chemistry Research: Used as a reference standard or starting material in hit-to-lead optimization and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Serves as a critical material for scaling up synthetic routes, optimizing yields, and developing robust manufacturing processes.
• Analytical Reference Standard: Employed in method development and validation for quality control (QC) and stability testing of developmental drug candidates.
• Biochemical Probe Development: Potential use in creating tool compounds for investigating specific biological targets and pathways in preclinical research.

Basic Information

Product Name	1-(2-((1R,3S,5R)-3-((2-fluoro-3-(trifluoromethoxy)phenyl)carbamoyl)-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)-5-methyl-1H-pyrazolo[3,4-c]pyridine-3-carboxamide benzoate
CAS No.	1528664-68-7
Molecular Formula	C31H26F4N6O5
Molecular Weight	638.57 g/mol
Synonyms	Benzoic acid, compd. with 1-[2-[3-[[[2-fluoro-3-(trifluoromethoxy)phenyl]amino]carbonyl]-2-azabicyclo[3.1.0]hex-2-yl]-2-oxoethyl]-5-methyl-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (1:1); UNII-4J7Q7K3I0F; 4J7Q7K3I0F; 1-(2-(3-((2-Fluoro-3-(trifluoromethoxy)phenyl)carbamoyl)-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)-5-methyl-1H-pyrazolo[3,4-c]pyridine-3-carboxamide benzoate; (1R,3S,5R)-2-(2-(3-Carbamoyl-5-methyl-1H-pyrazolo[3,4-c]pyridin-1-yl)acetyl)-N-(2-fluoro-3-(trifluoromethoxy)phenyl)-2-azabicyclo[3.1.0]hexane-3-carboxamide benzoate
EINECS	Contact for details

Quality Control

Our 1-(2-((1R,3S,5R)-3-((2-fluoro-3-(trifluoromethoxy)phenyl)carbamoyl)-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)-5-methyl-1H-pyrazolo[3,4-c]pyridine-3-carboxamide benzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications. We support compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates, ensuring the material is suitable for advanced research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.