Description

(33R,35S,91R,92R,5S,E)-5-(tert-butyl)-14,14-difluoro-4,7-dioxo-2,8,10-trioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopentanacyclotetradecaphan-12-ene-35-carboxylic acid is a sophisticated, high-purity organic compound designed for advanced research and development. This molecule is of significant interest due to its complex, multi-cyclic structure featuring a carboxylic acid group, difluoro substitution, and multiple heterocyclic systems, which are key motifs in modern pharmaceutical discovery. It serves as a critical building block or intermediate for medicinal chemists and process development scientists working in drug discovery, particularly for targeting challenging disease pathways.

Application

This advanced chemical intermediate is engineered for precision applications in life sciences research and development.

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs), especially for complex small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a sophisticated scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-up: Employed in the development and optimization of synthetic routes for potential drug candidates during preclinical and early-phase development.
• Biochemical Research: May be utilized as a tool compound or ligand in probing specific biological targets and enzymatic pathways due to its intricate structure.
• High-Purity Reference Standard: Can be supplied as a characterized standard for analytical method development and quality control in R&D laboratories.

Basic Information

Product Name	(33R,35S,91R,92R,5S,E)-5-(tert-butyl)-14,14-difluoro-4,7-dioxo-2,8,10-trioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopentanacyclotetradecaphan-12-ene-35-carboxylic acid
CAS No.	1365970-48-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5-(tert-Butyl)-14,14-difluoro-4,7-dioxo-2,8,10-trioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopentanacyclotetradecaphan-12-ene-35-carboxylic acid, (33R,35S,91R,92R,5S,E)-; CAS 1365970-48-4; Advanced Fluorinated Heterocyclic Intermediate; Complex Spirocyclic Carboxylic Acid Derivative; Pharmaceutical Building Block 1365970-48-4.
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management protocols. Every batch is characterized using advanced analytical techniques such as HPLC, NMR, and LC-MS to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profile is provided with each shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under inert atmosphere at lower temperatures (e.g., -20°C) to maximize stability. The container should be kept in a well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Single Unknown Impurity	≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.