Description

Methyl 3-Amino-6-Chloropyrazine-2-Carboxylate is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional structure, featuring both an amino group and a chloropyrazine moiety, which makes it a key intermediate for constructing complex nitrogen-containing molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various pharmacologically active compounds, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyrazine scaffold's bioactivity.
• Material Science Research: Serves as a building block for creating novel heterocyclic polymers, ligands, or organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 3-Amino-6-Chloropyrazine-2-Carboxylate
CAS No.	1458-03-3
Molecular Formula	C6H6ClN3O2
Molecular Weight	187.58 g/mol
Synonyms	Methyl 3-amino-6-chloropyrazine-2-carboxylate; 3-Amino-6-chloropyrazine-2-carboxylic acid methyl ester; 6-Chloro-3-aminopyrazine-2-carboxylic acid methyl ester; Methyl 6-chloro-3-aminopyrazine-2-carboxylate; 2-Pyrazinecarboxylic acid, 3-amino-6-chloro-, methyl ester; 3-Amino-6-chloro-2-pyrazinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-6-Chloropyrazine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.