Description

3-Amino-6-Iodopyrazine-2-Carboxylic Acid Methyl Ester is a versatile and highly functionalized heterocyclic building block, primarily valued for its role in advanced organic synthesis. Its unique structure, featuring both an amino and an iodo substituent on the pyrazine core, makes it a critical intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by serving as a core scaffold for bioactive molecules.
• Ligand Synthesis: Employed in the creation of specialized ligands for catalysis and materials science applications.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological pathways and protein interactions due to its modifiable functional groups.
• Advanced Material Development: Acts as a monomer or building block for synthesizing novel organic electronic materials and polymers.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse biaryl structures.

Basic Information

Product Name	3-Amino-6-Iodopyrazine-2-Carboxylic Acid Methyl Ester
CAS No.	1458-16-8
Molecular Formula	C6H6IN3O2
Molecular Weight	279.04 g/mol
Synonyms	Methyl 3-amino-6-iodopyrazine-2-carboxylate; 6-Iodo-3-aminopyrazine-2-carboxylic acid methyl ester; 3-Amino-6-iodo-2-pyrazinecarboxylic acid methyl ester; 2-Pyrazinecarboxylic acid, 3-amino-6-iodo-, methyl ester; Methyl 3-amino-6-iodo-2-pyrazinecarboxylate; AI3-52039; SCHEMBL11827579; BDBM50389385
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Iodopyrazine-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch consistency supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.