Description

Methyl 3-Amino-5,6-Dichloro-2-Pyrazinecarboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its core value lies in its functionalized pyrazine ring, which serves as a key intermediate in the development of complex active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific molecular complexity into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized nitrogen-containing ligands for catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and pigments due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring precise functionalization of the pyrazine core.
• Academic and R&D Laboratories: Used in exploratory chemistry to develop new synthetic methodologies and novel heterocyclic compounds.

Basic Information

Product Name	Methyl 3-Amino-5,6-Dichloro-2-Pyrazinecarboxylate
CAS No.	1458-18-0
Molecular Formula	C6H5Cl2N3O2
Molecular Weight	222.03 g/mol
Synonyms	Methyl 3-amino-5,6-dichloropyrazine-2-carboxylate; 5,6-Dichloro-3-aminopyrazine-2-carboxylic acid methyl ester; 3-Amino-5,6-dichloro-2-pyrazinecarboxylic acid methyl ester; Methyl 3-amino-5,6-dichloro-2-pyrazinecarboxylate; 2-Pyrazinecarboxylic acid, 3-amino-5,6-dichloro-, methyl ester; Methyl 5,6-dichloro-3-aminopyrazine-2-carboxylate; 1458-18-0; CAS 1458-18-0
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-5,6-Dichloro-2-Pyrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the potential for light sensitivity and moisture absorption, containers should be kept sealed under an inert atmosphere when not in use for extended periods.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC Area %)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.