Description

Methyl 3-Amino-6-Chloro-5-[(Cyclopropylmethyl)Amino]Pyrazine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrazine-carboxylate structure. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug molecules, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex pyrazine-based molecular architectures.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of client-specific APIs under cGMP conditions.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Methyl 3-Amino-6-Chloro-5-[(Cyclopropylmethyl)Amino]Pyrazine-2-Carboxylate
CAS No.	1144-56-5
Molecular Formula	C10H13ClN4O2
Molecular Weight	256.69 g/mol
Synonyms	Methyl 3-Amino-6-Chloro-5-(cyclopropylmethylamino)pyrazine-2-carboxylate; 3-Amino-6-chloro-5-[(cyclopropylmethyl)amino]-2-pyrazinecarboxylic acid methyl ester; 5-[(Cyclopropylmethyl)amino]-3-amino-6-chloropyrazine-2-carboxylic acid methyl ester; Methyl 3-amino-6-chloro-5-(N-cyclopropylmethylamino)pyrazine-2-carboxylate; 1144-56-5; Pyrazine-2-carboxylic acid, 3-amino-6-chloro-5-[(cyclopropylmethyl)amino]-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-6-Chloro-5-[(Cyclopropylmethyl)Amino]Pyrazine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.