Description

[(3S)-oxolan-3-yl] N-[(2S,3S)-4-[(2S)-2-benzyl-4-[(2S)-2-(2-methylpropyl)-3-oxo-4-[(1R)-2-phenyl-1-(tert-butylcarbamoyl)ethyl]-1H-pyrrol-2-yl]-3-oxo-1H-pyrrol-2-yl]-3-hydroxy-1-phenyl-butan-2-yl]carbamate is a sophisticated, high-purity chiral compound designed for advanced pharmaceutical research and development. This complex molecule serves as a critical intermediate or building block in the synthesis of novel therapeutic agents, particularly in the fields of oncology and metabolic disease. It is essential for pharmaceutical manufacturers and contract research organizations (CROs) engaged in the discovery and process development of peptide-mimetic and protease inhibitor drugs.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development of novel inhibitors targeting specific enzymes involved in disease pathways.
• Peptidomimetic Drug Discovery: Serves as a core scaffold for creating stable, bioavailable mimics of natural peptide structures.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial manufacturing of target molecules.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in API production.
• Academic & Institutional Research: Used in chemical biology and medicinal chemistry programs to study structure-activity relationships (SAR).

Basic Information

Item	Details
Product Name	[(3S)-oxolan-3-yl] N-[(2S,3S)-4-[(2S)-2-benzyl-4-[(2S)-2-(2-methylpropyl)-3-oxo-4-[(1R)-2-phenyl-1-(tert-butylcarbamoyl)ethyl]-1H-pyrrol-2-yl]-3-oxo-1H-pyrrol-2-yl]-3-hydroxy-1-phenyl-butan-2-yl]carbamate
CAS No.	173091-97-9
Molecular Formula	C48H56N4O7
Molecular Weight	800.99 g/mol
Synonyms	(3S)-Tetrahydrofuran-3-yl (2S,3S)-4-[(2S)-2-benzyl-4-[(2S)-2-isobutyl-3-oxo-4-[(1R)-2-phenyl-1-[(tert-butylamino)carbonyl]ethyl]-1H-pyrrol-2-yl]-3-oxo-1H-pyrrol-2-yl]-3-hydroxy-1-phenylbutan-2-ylcarbamate; Chiral Pyrrolidinone Derivative; Advanced Peptidomimetic Scaffold; Pharmaceutical Building Block 173091-97-9; tert-Butyl [(1R)-1-[(2S)-2-[(2S)-2-benzyl-5-[(2S,3S)-3-hydroxy-1-phenyl-2-[[[(3S)-oxolan-3-yl]oxycarbonyl]amino]butyl]-3-oxo-1H-pyrrol-1-yl]-4-methyl-1-oxopentan-2-yl]-2-phenylethyl]carbamate
EINECS	Contact for details

Quality Control

Our [(3S)-oxolan-3-yl] N-[(2S,3S)-4-[(2S)-2-benzyl-4-[(2S)-2-(2-methylpropyl)-3-oxo-4-[(1R)-2-phenyl-1-(tert-butylcarbamoyl)ethyl]-1H-pyrrol-2-yl]-3-oxo-1H-pyrrol-2-yl]-3-hydroxy-1-phenyl-butan-2-yl]carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing chiral purity, assay, and impurity profiles are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.