Description

4-[(3S,5R,8R,9S,10S,13R,14S,17S)-10,13-dimethyl-3-[(2R,3R,4S,5R,6R)-3, 4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,5,6,7,8,9,11,12,14 ,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-5H-furan-2 -one is a high-purity steroidal lactone derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for synthesizing novel therapeutic agents targeting hormone-related pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) working in endocrinology, oncology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroidal drugs and hormone analogs.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in API manufacturing.
• Biochemical Research: Tool compound for studying steroid receptor interactions, enzyme inhibition, and metabolic pathways in vitro.
• Preclinical Development: Used in the discovery and early-stage development of therapeutics for cancers, metabolic disorders, and inflammatory conditions.
• Process Chemistry: Serves as a starting material or advanced intermediate in scalable, GMP-compliant synthetic routes.

Basic Information

Product Name	4-[(3S,5R,8R,9S,10S,13R,14S,17S)-10,13-dimethyl-3-[(2R,3R,4S,5R,6R)-3, 4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3,4,5,6,7,8,9,11,12,14 ,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-5H-furan-2 -one
CAS No.	102492-19-3
Molecular Formula	C30H44O7
Molecular Weight	516.67 g/mol
Synonyms	Digitoxigenin β-D-glucoside; Digitoxigenin glucoside; 3β-(β-D-Glucopyranosyloxy)-14-hydroxy-5β-card-20(22)-enolide; (3β,5β)-3-(β-D-Glucopyranosyloxy)-14-hydroxycard-20(22)-enolide; Strophanthidin 3-O-β-D-glucoside; Corchoroside A (partial); CAS 102492-19-3
EINECS	Contact for details

Quality Control

Every batch of our steroidal lactone products undergoes rigorous quality testing to ensure identity, purity, and consistency. Our quality systems are designed to meet the exacting standards of pharmaceutical development. Certificates of Analysis (COA) are provided with each shipment, detailing results for key parameters such as assay, related substances, and residual solvents. We support compliance with ICH guidelines and can supply materials suitable for use under GMP conditions upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.