Description

(E)-2-Hydroxymethyl-2-butenoic acid (E)-2-[[[(3aR)-2,3,3aβ,4,5,6,6aβ,7,9aβ,9bα-decahydro-7α-hydroxy-9-methyl-3,6-bismethylene-2-oxoazuleno[4,5-b]furan-4α-yl]oxy]carbonyl]-2-butenyl ester is a high-purity, complex organic ester with a defined stereochemistry, serving as a critical advanced intermediate in sophisticated chemical syntheses. Its intricate molecular architecture makes it a valuable building block for research and development in specialized pharmaceutical and agrochemical applications. This compound is essential for chemists and R&D teams in the fine chemical, pharmaceutical, and life science sectors seeking to develop novel active ingredients or complex natural product derivatives.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of novel drug candidates, particularly for complex small-molecule therapeutics.
• Agrochemical Synthesis: Used as a building block in the development of advanced pesticides, herbicides, or plant growth regulators with specific stereochemical requirements.
• Chemical Research: Serves as a model compound or a critical reagent in methodological studies and total synthesis projects within academic and industrial R&D laboratories.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, specialty chemicals where its specific ester and olefin functionalities are required.
• Natural Product Analog Development: Useful for synthesizing analogs or derivatives of complex natural products for structure-activity relationship (SAR) studies.

Basic Information

Product Name	(E)-2-Hydroxymethyl-2-butenoic acid (E)-2-[[[(3aR)-2,3,3aβ,4,5,6,6aβ,7,9aβ,9bα-decahydro-7α-hydroxy-9-methyl-3,6-bismethylene-2-oxoazuleno[4,5-b]furan-4α-yl]oxy]carbonyl]-2-butenyl ester
CAS No.	100015-12-1
Molecular Formula	C24H30O8
Molecular Weight	446.49 g/mol
Synonyms	2-Butenoic acid, 2-(hydroxymethyl)-, (E)-, (3aR,4S,6aS,7R,9aS,9bR)-decahydro-7-hydroxy-9-methyl-3,6-bis(methylene)-2-oxoazuleno[4,5-b]furan-4-yl ester, (E)-; (E)-2-(Hydroxymethyl)-2-butenoic acid ester with guaian-6,12-olide derivative; A derivative of 2-Hydroxymethylcrotonic acid; Complex Guaianolide Ester.
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. All material is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with relevant cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term stability, storage at 2-8°C (refrigerated) is recommended. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.