Description

Benzyl 3-Aminopiperidine-1-Carboxylate Hydrochloride is a high-purity, protected piperidine derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile chiral intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the piperidine scaffold contributes to biological activity.
• Peptidomimetics & Bioactive Molecule Synthesis: The protected amine and carboxylate groups make it ideal for constructing peptide analogs and other complex bioactive structures.
• Chemical Library Development: Employed in combinatorial chemistry and high-throughput screening for generating diverse compound libraries in drug discovery programs.
• Catalyst & Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Process Chemistry: A valuable reagent for methodological development in organic synthesis and scale-up process optimization.

Basic Information

Product Name	Benzyl 3-Aminopiperidine-1-Carboxylate Hydrochloride
CAS No.	960541-42-8
Molecular Formula	C13H19ClN2O2
Molecular Weight	270.75 g/mol
Synonyms	1-Carbobenzyloxy-3-aminopiperidine hydrochloride; 3-Amino-1-CBZ-piperidine hydrochloride; Benzyl 3-amino-1-piperidinecarboxylate hydrochloride; 1-(Benzyloxycarbonyl)-3-aminopiperidine hydrochloride; 3-Amino-N-CBZ-piperidine HCl; 3-Aminopiperidine-1-carboxylic acid benzyl ester hydrochloride; 1-CBZ-3-aminopiperidine HCl; 3-Amino-1-piperidinecarboxylic acid phenylmethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Benzyl 3-Aminopiperidine-1-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for advanced synthetic intermediates. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.