Description

2,5-Diketo-3,6-Di(4-Succinylaminobutyl) Piperazine is a specialized piperazine derivative with a unique bifunctional succinylaminobutyl structure. This compound serves as a high-value chemical building block and cross-linking agent in advanced material synthesis. It is primarily utilized by R&D and production teams in the pharmaceutical, polymer, and specialty chemical industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex active pharmaceutical ingredients (APIs) and prodrugs, particularly those requiring specific linker chemistry.
• Polymer Cross-Linking Agent: Functions as a reactive monomer to introduce amide linkages and enhance the thermal stability and mechanical properties of specialty polymers and resins.
• Bioconjugation Reagent: Employed in the development of antibody-drug conjugates (ADCs) and other biopharmaceuticals due to its reactive succinyl groups for attaching payloads.
• Dendrimer and Macromolecule Synthesis: Acts as a core or branching unit in the construction of dendrimers and other precisely structured macromolecules.
• Material Science Research: Serves as a precursor for developing novel coatings, hydrogels, and smart materials with responsive characteristics.
• Peptide Mimetic Chemistry: Used to create peptidomimetics and constrained analogs in medicinal chemistry programs.

Basic Information

Product Name	2,5-Diketo-3,6-Di(4-Succinylaminobutyl) Piperazine
CAS No.	176738-91-3
Molecular Formula	C22H36N4O8
Molecular Weight	484.55 g/mol
Synonyms	3,6-Bis(4-succinylaminobutyl)-2,5-diketopiperazine; 2,5-Piperazinedione, 3,6-bis[4-[(3-carboxy-1-oxopropyl)amino]butyl]-; 3,6-Bis(4-succinylaminobutyl)piperazine-2,5-dione; N,N'-(Dibutan-4,1-diyl)bis[4-(2,5-dioxopyrrolidin-1-yl)butanamide] (related structure); Succinylaminobutyl Diketopiperazine Derivative
EINECS	Contact for details

Quality Control

Our 2,5-Diketo-3,6-Di(4-Succinylaminobutyl) Piperazine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-grade production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.