Description

1-Methyl-4-(3-Chloropropyl)Piperazine is a versatile and reactive bifunctional organic intermediate featuring both a piperazine ring and a chloropropyl side chain. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those targeting the central nervous system (CNS) and as building blocks for kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the piperazine moiety imparts specific biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent for producing specialty polymers with tailored properties.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.
• Dye and Pigment Manufacturing: Utilized in the synthesis of specialized colorants and photographic chemicals.

Basic Information

Product Name	1-Methyl-4-(3-Chloropropyl)Piperazine
CAS No.	104-16-5
Molecular Formula	C8H17ClN2
Molecular Weight	176.69 g/mol
Synonyms	N-Methyl-N'-(3-chloropropyl)piperazine; 1-(3-Chloropropyl)-4-methylpiperazine; 3-Chloropropyl Methylpiperazine; 4-Methyl-1-(3-chloropropyl)piperazine; N-(3-Chloropropyl)-N'-methylpiperazine; 1-Methyl-4-(γ-chloropropyl)piperazine; 104-16-5; Methyl(3-chloropropyl)piperazine
EINECS	203-182-8

Quality Control

Our 1-Methyl-4-(3-Chloropropyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopic methods, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the reactive chloroalkyl group, it should be stored separately from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.05 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.